What is a Loss? Loss[los]noun1.A Loss is an injury or damage that is covered by an insurance Policy. Losses can be partial, like when wind damages part of a roof, or total, as when an automobile is “totaled” in a collision. Share | Have A Question About This Topic? Address Thank you! Oops! Related Contents If You're In An Accident Do you know what to do if you're in a car accident? What You Should Do About Insurance Following a Divorce In the face of divorce, making changes to insurance coverage may be overlooked. Long-Term-Care Protection Strategies The chances of needing long-term care, its cost, and strategies for covering that cost.